Article
Characterizing Transcriptional Regulatory Sequences in Coronaviruses and Their Role in Recombination
2 Nov 2020
Abstract excerpt
Novel coronaviruses, including SARS-CoV-2, SARS, and MERS, often originate from recombination events. The mechanism of recombination in RNA viruses is template switching. Coronavirus transcription also involves template switching at specific regions, called transcriptional regulatory sequences (TRS). It is hypothesized but not yet verified that TRS sites are prone to recombination events. Here, we developed a...
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