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Article

Specific induction and long-term maintenance of high purity ventricular cardiomyocytes from human induced pluripotent stem cells

2 Nov 2020

Abstract excerpt

Currently, cardiomyocyte (CM) differentiation methods require a purification step after CM induction to ensure the high purity of the cell population. Here we show an improved human CM differentiation protocol with which high-purity ventricular-type CMs can be obtained and maintained without any CM purification process. We induced and collected a mesodermal cell population (platelet-derived growth factor...

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PMID: 33137106
DOI: 10.1371/journal.pone.0241287

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