Identifying an oligometastatic phenotype in HPV-associated oropharyngeal squamous cell cancer: Implications for clinical trial design.

doi:10.1016/j.oraloncology.2020.105046

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Article

Identifying an oligometastatic phenotype in HPV-associated oropharyngeal squamous cell cancer: Implications for clinical trial design.

Oral oncology - 1 Jan 2021

Fleming Christopher W, Ward Matthew C, Woody Neil M, Joshi Nikhil P, Greskovich John F, Rybicki Lisa, Xiong David, Contrera Kevin, Chute Deborah J, Milas Zvonimir L, Frenkel Catherine H, Brickman Daniel S, Carrizosa Daniel R, Ku Jamie, Prendes Brandon, Lamarre Eric, Lorenz Robert R, Scharpf Joseph, Burkey Brian B, Schwartzman Larisa, Geiger Jessica L, Adelstein David J, Koyfman Shlomo A

Abstract excerpt

OBJECTIVES: Patients with human papillomavirus (HPV) associated squamous cell carcinoma of the oropharynx (SCC-OP) have improved overall survival (OS) after distant metastasis (DM) compared to HPV negative patients. These patients may be appropriate candidates for enrollment on clinical trials evaluating the efficacy of metastasis-directed therapy (MDT). This study seeks to identify prognostic factors associated...

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PMID: 33129058
DOI: 10.1016/j.oraloncology.2020.105046

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