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Article

The N-terminal residual arginine19 of influenza A virus NS1 protein is required for its nuclear localization and RNA binding.

Veterinary microbiology - 1 Dec 2020

Wang Xingbo, Lin Lulu, Yu Yang, Yan Yan, Ojha Nishant Kumar, Zhou Jiyong

Abstract excerpt

RNA binding ability and cellular distribution are important for nonstructural protein 1 (NS1) of influenza A virus to act as a viral regulatory factor to control virus life cycle. In this study, we identified that the N-terminal residues 19-21 of NS1 are a highly conserved motif depending on all the available NS1 full length sequence of H5N1 influenza A virus from NCBI database. Site-directed mutation analysis...

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Source

Identifiers

PMID: 33126184
DOI: 10.1016/j.vetmic.2020.108895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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