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Identifying Candidate Genetic Markers of CDV Cross-Species Pathogenicity in African Lions

23 Oct 2020

Abstract excerpt

Canine distemper virus (CDV) is a multi-host pathogen with variable clinical outcomes of infection across and within species. We used whole-genome sequencing (WGS) to search for viral markers correlated with clinical distemper in African lions. To identify candidate markers, we first documented single-nucleotide polymorphisms (SNPs) differentiating CDV strains associated with different clinical outcomes in lions...

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PMID: 33114123
DOI: 10.3390/pathogens9110872

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