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Article

Expresser phenotype determines ABO(H) blood group antigen loading on platelets and von Willebrand factor.

Scientific reports - 27 Oct 2020

O'Donghaile Diarmaid, Jenkins P Vincent, McGrath Rachel T, Preston Lisa, Field Stephen P, Ward Soracha E, O'Sullivan Jamie M, O'Donnell James S

Abstract excerpt

ABO blood group is associated with cardiovascular disease, with significantly lower risk in blood group O individuals. ABO(H) blood group determinants are expressed on different glycoproteins on platelet surfaces. In addition, ABO(H) structures are also present on VWF glycans. These ABO(H) carbohydrates influence both platelet and VWF function. Previous studies have reported that approximately 5-10% of normal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33110150
DOI: 10.1038/s41598-020-75462-2
PMCID: PMC7591562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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