Article
ESR1 gene variants, haplotypes and diplotypes may influence the risk of breast cancer and mammographic density.
Molecular biology reports - 1 Nov 2020
Khorshid Shamshiri Asma, Afzaljavan Fahimeh, Alidoust Maryam, Taherian Vahideh, Vakili Fatemeh, Moezzi Atefeh, Homaei Shandiz Fatemeh, Farrokh Donya, Pasdar Alireza
Abstract excerpt
Breast cancer as the most common cancer worldwide is influenced by genetic and physiological factors. Based on some evidence indicating the role of estrogen receptor 1 gene (ESR1) in breast cancer development, in this study, the association of three common variations in ESR1 gene with breast cancer and density in an Iranian population was evaluated. In a case-control study, 400 blood samples were collected for...
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