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Article

Establishment and validation of immune microenvironmental gene signatures for predicting prognosis in patients with head and neck squamous cell carcinoma.

International immunopharmacology - 1 Aug 2021

Wang Juncheng, Tian Yuxi, Zhu Gangcai, Li Zhexuan, Wu Zhisheng, Wei Guifang, Zhuang Liming, Li Zhonghua, Chen Xun, Zhang Xin, Zheng Jinyang, Cai Gengming

Abstract excerpt

Tumor cells influencing the microenvironment are essential for restrained immunity in head and neck squamous cell carcinoma (HNSCC). There has been considerable progress in the research on monoclonal antibodies for antigen-specific immunotherapy that overcome immunosuppressive checkpoint receptor/ligand signaling in patients with HNSCC. However, alteration of immunogenicity and formation of neoantigens that lead...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34091115
DOI: 10.1016/j.intimp.2021.107817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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