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Article

Oxidative Stress Profile in Genetically Confirmed Cases of Leber's Hereditary Optic Neuropathy.

Journal of molecular neuroscience : MN - 1 May 2021

Rovcanin Branislav, Jancic Jasna, Pajic Jelena, Rovcanin Marija, Samardzic Janko, Djuric Vesna, Nikolic Blazo, Ivancevic Nikola, Novakovic Ivana, Kostic Vladimir

Abstract excerpt

The mechanisms of the complex pathophysiology of Leber's hereditary optic neuropathy (LHON) are still insufficiently clarified. The role of oxidative stress as an etiological factor has been proposed and demonstrated in vitro, but without conclusive data that rely on clinical samples. The aim of the study was to evaluate and characterize the existence of oxidative stress in the plasma of LHON patients and healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33095398
DOI: 10.1007/s12031-020-01729-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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