Article
Effects of SARS-CoV-2 mutations on protein structures and intraviral protein-protein interactions.
Journal of medical virology - 1 Apr 2021
Wu Siqi, Tian Chang, Liu Panpan, Guo Dongjie, Zheng Wei, Huang Xiaoqiang, Zhang Yang, Liu Lijun
Abstract excerpt
Since 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) has infected 10 millions of people across the globe, and massive mutations in virus genome have occurred during the rapid spread of this novel coronavirus. Variance in protein sequence might lead to a change in protein structure and interaction, then further affect the viral physiological...
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