Article
Manipulation of the gut microbiota by the use of prebiotic fibre does not override a genetic predisposition to heart failure.
Scientific reports - 21 Oct 2020
Jama Hamdi A, Fiedler April, Tsyganov Kirill, Nelson Erin, Horlock Duncan, Nakai Michael E, Kiriazis Helen, Johnson Chad, Du Xiao-Jun, Mackay Charles R, Marques Francine Z, Kaye David M
Abstract excerpt
Increasing evidence supports a role for the gut microbiota in the development of cardiovascular diseases such as hypertension and its progression to heart failure (HF). Dietary fibre has emerged as a modulator of the gut microbiota, resulting in the release of gut metabolites called short-chain fatty acids (SCFAs), such as acetate. We have shown previously that fibre or acetate can protect against hypertension...
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