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Genome sequencing and phylogenetic reconstruction reveal a potential fourth rhinovirus species and its worldwide distribution.

Archives of virology - 1 Jan 2021

Ng Kim Tien, Takebe Yutaka, Kamarulzaman Adeeba, Tee Kok Keng

Abstract excerpt

Genome sequences of members of a potential fourth rhinovirus (RV) species, provisionally denoted as rhinovirus A clade D, from patients with acute respiratory infection were determined. Bayesian coalescent analysis estimated that clade D emerged around the 1940s and diverged further around 2006-2007 into two distinctive sublineages (RV-A8-like and RV-A45-like) that harbored unique "clade-defining" substitutions....

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PMID: 33084935
DOI: 10.1007/s00705-020-04855-5

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