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Role of Mitofusins and Mitophagy in Life or Death Decisions

22 Sept 2020

Abstract excerpt

Mitochondria entail an incredible dynamism in their morphology, impacting death signaling and selective elimination of the damaged organelles. In turn, by recycling the superfluous or malfunctioning mitochondria, mostly prevalent during aging, mitophagy contributes to maintain a healthy mitochondrial network. Mitofusins locate at the outer mitochondrial membrane and control the plastic behavior of mitochondria,...

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PMID: 33072754
DOI: 10.3389/fcell.2020.572182

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