Article
False Positive Multiparametric Magnetic Resonance Imaging Phenotypes in the Biopsy-naïve Prostate: Are They Distinct from Significant Cancer-associated Lesions? Lessons from PROMIS.
European urology - 1 Jan 2021
Stavrinides Vasilis, Syer Tom, Hu Yipeng, Giganti Francesco, Freeman Alex, Karapanagiotis Solon, Bott Simon R J, Brown Louise C, Burns-Cox Nicholas, Dudderidge Timothy J, Bosaily Ahmed El-Shater, Frangou Elena, Ghei Maneesh, Henderson Alastair, Hindley Richard G, Kaplan Richard S, Oldroyd Robert, Parker Chris, Persad Raj, Rosario Derek J, Shergill Iqbal S, Echeverria Lina M Carmona, Norris Joseph M, Winkler Mathias, Barratt Dean, Kirkham Alex, Punwani Shonit, Whitaker Hayley C, Ahmed Hashim U, Emberton Mark
Abstract excerpt
BACKGROUND: False positive multiparametric magnetic resonance imaging (mpMRI) phenotypes prompt unnecessary biopsies. The Prostate MRI Imaging Study (PROMIS) provides a unique opportunity to explore such phenotypes in biopsy-naïve men with raised prostate-specific antigen (PSA) and suspected cancer. OBJECTIVE: To compare mpMRI lesions in men with/without significant cancer on transperineal mapping biopsy (TPM)....
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