Article
Integrative network analysis identifies an immune-based prognostic signature as the determinant for the mesenchymal subtype in epithelial ovarian cancer.
Medicine - 9 Oct 2020
Sheng Mingyan, Tong Haofei, Lu Xiaoyan, Shanshan Ni, Zhang Xingguo, Reddy B Ashok, Shu Peng
Abstract excerpt
BACKGROUND: Epithelial ovarian cancer (EOC) has been classified into four molecular subtypes, of which the mesenchymal subtype has the poorest survival. Our goal is to develop an immune-based prognostic signature by incorporating molecular subtypes for EOC patients. METHODS: The gene expression profiles of EOC samples were collected from seven public datasets as well as an internal retrospective validation...
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