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In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition

7 Oct 2020

Abstract excerpt

The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which these core programs are distinct, overlapping, or identical has remained undefined. Here, we triggered partial EMT (pEMT) or UJT in differentiated primary human bronchial epithelial cells. After triggering UJT, cell-cell junctions,...

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PMID: 33028821
DOI: 10.1038/s41467-020-18841-7

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