Article
Plasma metanephrines and prospective prediction of tumor location, size and mutation type in patients with pheochromocytoma and paraganglioma.
Clinical chemistry and laboratory medicine - 1 Oct 2020
Eisenhofer Graeme, Deutschbein Timo, Constantinescu Georgiana, Langton Katharina, Pamporaki Christina, Calsina Bruna, Monteagudo Maria, Peitzsch Mirko, Fliedner Stephanie, Timmers Henri J L M, Bechmann Nicole, Fankhauser Maria, Nölting Svenja, Beuschlein Felix, Stell Anthony, Fassnacht Martin, Prejbisz Aleksander, Lenders Jacques W M, Robledo Mercedes
Abstract excerpt
Objectives: Plasma free metanephrines are commonly used for diagnosis of pheochromocytoma and paraganglioma (PPGLs), but can also provide other information. This multicenter study prospectively examined whether tumor size, location, and mutations could be predicted by these metabolites. Methods: Predictions of tumor location, size, and mutation type, based on measurements of plasma normetanephrine, metanephrine,...
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