Article
Increased level of cathelicidin (LL-37) in vitiligo: Possible pathway independent from vitamin D receptor gene polymorphism.
Experimental dermatology - 1 Dec 2020
Atazadeh Fatemeh, Fazeli Zahra, Vahidnezhad Hassan, Namazi Nastaran, Younespour Shima, Youssefian Leila, Abdollahimajd Fahimeh, Uitto Jouni
Abstract excerpt
Vitiligo is a multifactorial skin disease with established role of genetics and autoimmunity in its pathogenesis. Vitamin D receptor (VDR) polymorphisms have been suggested to correlate with risk of vitiligo in some ethnic populations. On the other hand, cathelicidin, one of the innate immune system components, has a role in development of some chronic skin diseases and VDR regulates the expression of...
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