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Article

Clinical and analytical validation of FoundationOne Liquid CDx, a novel 324-Gene cfDNA-based comprehensive genomic profiling assay for cancers of solid tumor origin.

PloS one - 1 Jan 2020

Woodhouse Ryan, Li Meijuan, Hughes Jason, Delfosse David, Skoletsky Joel, Ma Pei, Meng Wei, Dewal Ninad, Milbury Coren, Clark Travis, Donahue Amy, Stover Dan, Kennedy Mark, Dacpano-Komansky Jennifer, Burns Christine, Vietz Christine, Alexander Brian, Hegde Priti, Dennis Lucas

Abstract excerpt

As availability of precision therapies expands, a well-validated circulating cell-free DNA (cfDNA)-based comprehensive genomic profiling assay has the potential to provide considerable value as a complement to tissue-based testing to ensure potentially life-extending therapies are administered to patients most likely to benefit. Additional data supporting the clinical validity of cfDNA-based testing is necessary...

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Identifiers

PMID: 32976510
DOI: 10.1371/journal.pone.0237802
PMCID: PMC7518588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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