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Article

Roles of the Tol-Pal system in the Type III secretion system and flagella-mediated virulence in enterohemorrhagic Escherichia coli.

Scientific reports - 23 Sept 2020

Hirakawa Hidetada, Suzue Kazutomo, Takita Ayako, Awazu Chikako, Kurushima Jun, Tomita Haruyoshi

Abstract excerpt

The Tol-Pal system is a protein complex that is highly conserved in many gram-negative bacteria. We show here that the Tol-Pal system is associated with the enteric pathogenesis of enterohemorrhagic E. coli (EHEC). Deletion of tolB, which is required for the Tol-Pal system decreased motility, secretion of the Type III secretion system proteins EspA/B, and the ability of bacteria to adhere to and to form attaching...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32968151
DOI: 10.1038/s41598-020-72412-w
PMCID: PMC7511404

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