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Integration of genetic variants and gene network for drug repurposing in colorectal cancer.

Pharmacological research - 1 Nov 2020

Irham Lalu Muhammad, Wong Henry Sung-Ching, Chou Wan-Hsuan, Adikusuma Wirawan, Mugiyanto Eko, Huang Wan-Chen, Chang Wei-Chiao

Abstract excerpt

Even though many genetic risk loci for human diseases have been identified and comprehensively cataloged, strategies to guide clinical research by integrating the extensive results of genetic studies and biological resources are still limited. Moreover, integrative analyses that provide novel insights into disease biology are expected to be especially useful for drug discovery. Herein, we used text mining of...

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PMID: 32950641
DOI: 10.1016/j.phrs.2020.105203

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