Article
A multi-objective optimization method for identification of module biomarkers for disease diagnosis.
Methods (San Diego, Calif.) - 1 Aug 2021
Su Yansen, Su Xiaochun, Wang Qijun, Zhang Lejun
Abstract excerpt
Biomarker identification aims at finding a set of biological indicators that best discriminate biological samples of different phenotypes. In this paper, we take the module containing the significant disease-related genes and their interactions from biological networks as a module biomarker, and propose an evolutionary multi-objective optimization method to identify module biomarkers for disease diagnosis. To be...
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