Article
Edge biomarkers for classification and prediction of phenotypes.
Science China. Life sciences - 1 Nov 2014
Zeng Tao, Zhang WanWei, Yu XiangTian, Liu XiaoPing, Li MeiYi, Liu Rui, Chen LuoNan
Abstract excerpt
In general, a disease manifests not from malfunction of individual molecules but from failure of the relevant system or network, which can be considered as a set of interactions or edges among molecules. Thus, instead of individual molecules, networks or edges are stable forms to reliably characterize complex diseases. This paper reviews both traditional node biomarkers and edge biomarkers, which have been newly...
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