Article
TIE1 as a Candidate Gene for Lymphatic Malformations with or without Lymphedema.
International journal of molecular sciences - 16 Sept 2020
Michelini Sandro, Ricci Maurizio, Veselenyiova Dominika, Kenanoglu Sercan, Kurti Danjela, Baglivo Mirko, Fiorentino Alessandro, Basha Syed Hussain, Priya Sasi, Serrani Roberta, Krajcovic Juraj, Dundar Munis, Dautaj Astrit, Bertelli Matteo
Abstract excerpt
TIE1 is a cell surface protein expressed in endothelial cells. Involved in angiogenesis and lymphangiogenesis, including morphogenesis of lymphatic valves, TIE1 is important for lymphatic system functional integrity. The main purpose of this study was to identify different variants in the TIE1 gene that could be associated with lymphatic malformations or dysfunction and predisposition for lymphedema. In a cohort...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.