Article
Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project.
Nature reviews. Nephrology - 1 Nov 2020
Ong Edison, Wang Lucy L, Schaub Jennifer, O'Toole John F, Steck Becky, Rosenberg Avi Z, Dowd Frederick, Hansen Jens, Barisoni Laura, Jain Sanjay, de Boer Ian H, Valerius M Todd, Waikar Sushrut S, Park Christopher, Crawford Dana C, Alexandrov Theodore, Anderton Christopher R, Stoeckert Christian, Weng Chunhua, Diehl Alexander D, Mungall Christopher J, Haendel Melissa, Robinson Peter N, Himmelfarb Jonathan, Iyengar Ravi, Kretzler Matthias, Mooney Sean, He Yongqun
Abstract excerpt
An important need exists to better understand and stratify kidney disease according to its underlying pathophysiology in order to develop more precise and effective therapeutic agents. National collaborative efforts such as the Kidney Precision Medicine Project are working towards this goal through the collection and integration of large, disparate clinical, biological and imaging data from patients with kidney...
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