Article
Genetic variants in MIR2113 and MIR129-LEP are associated with the susceptibility of COPD in the Chinese Han population.
Pulmonary pharmacology & therapeutics - 1 Oct 2020
Jing Jing, Xu Dan, Li Zheng, Jiang Min, Wang Jing, Zhang Jian
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the result of interaction between genetic and environmental factors. In this study, we aimed to explore whether MIR2113 and MIR129-LEP polymorphisms confer susceptibility to COPD. METHODS: We selected five polymorphisms of two genes (MIR2113: rs2505059 and rs9320913; MIR129-LEP: rs7778167, rs791595 and rs4731420) based on previous studies and genotyped...
