Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Pan-cancer analysis of alternative splicing regulator heterogeneous nuclear ribonucleoproteins (hnRNPs) family and their prognostic potential.

Journal of cellular and molecular medicine - 1 Oct 2020

Li Hao, Liu Jingwei, Shen Shixuan, Dai Di, Cheng Shitong, Dong Xiaolong, Sun Liping, Guo Xiaolin

Abstract excerpt

As the most critical alternative splicing regulator, heterogeneous nuclear ribonucleoproteins (hnRNPs) have been reported to be implicated in various aspects of cancer. However, the comprehensive understanding of hnRNPs in cancer is still lacking. The molecular alterations and clinical relevance of hnRNP genes were systematically analysed in 33 cancer types based on next-generation sequence data. The expression,...

Topics

Alternative Splicing
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Heterogeneous-Nuclear Ribonucleoproteins
Humans
Mutation
Neoplasms
Prognosis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 32915499
DOI: 10.1111/jcmm.15558
PMCID: PMC7576281

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pan-cancer analysis of alternative splicing regulator heterogeneous nuclear ribonucleoproteins (hnRNPs) family and their prognostic potential.PMID 32915499Read ↗

Whole Genome Analysis and Prognostic Model Construction Based on Alternative Splicing Events in Endometrial CancerSemantic proximity Read ↗

Pan-cancer Analysis Reveals the Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) Its Significance in Human CancersSemantic proximity Read ↗

The hnRNP family: insights into their role in health and diseaseSemantic proximity Read ↗

The Potential Impact of HNRNPA2B1 on Human Cancers Prognosis and Immune Microenvironment.Semantic proximity Read ↗

Tilte：SNRPA may mediate transcription and splicing of genesassociated with HCC via binding special RNAsSemantic proximity Read ↗

An integrative RNA spliceosomic landscape of pancreatic neuroendocrine tumors unveils novel clinicomolecular associationsSemantic proximity Read ↗

Comprehensive analysis of the expression and prognostic value for SNRP members in hepatocellular carcinomaSemantic proximity Read ↗

Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networksSemantic proximity Read ↗

Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks.Semantic proximity Read ↗

Integrated Analysis of Proteome and Transcriptome Profiling Reveals Pan-Cancer-Associated Pathways and Molecular BiomarkersSemantic proximity Read ↗

Regulation of AUF1 alternative splicing by hnRNPA1 and SRSF2 modulate the sensitivity of ovarian cancer cells to cisplatinSemantic proximity Read ↗

A pan-cancer analysis of alternative splicing of splicing factors in 6904 patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.