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Article

MosaicBase: A Knowledgebase of Postzygotic Mosaic Variants in Noncancer Disease-related and Healthy Human Individuals.

Genomics, proteomics & bioinformatics - 1 Apr 2020

Yang Xiaoxu, Yang Changhong, Zheng Xianing, Xiong Luoxing, Tao Yutian, Wang Meng, Ye Adam Yongxin, Wu Qixi, Dou Yanmei, Luo Junyu, Wei Liping, Huang August Yue

Abstract excerpt

Mosaic variants resulting from postzygotic mutations are prevalent in the human genome and play important roles in human diseases. However, except for cancer-related variants, there is no collection of postzygotic mosaic variants in noncancer disease-related and healthy individuals. Here, we present MosaicBase, a comprehensive database that includes 6698 mosaic variants related to 266 noncancer diseases and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32911083
DOI: 10.1016/j.gpb.2020.05.002
PMCID: PMC7646124

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