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Article

Visceral Mechano-sensing Neurons Control Drosophila Feeding by Using Piezo as a Sensor.

Neuron - 25 Nov 2020

Wang Pingping, Jia Yinjun, Liu Ting, Jan Yuh-Nung, Zhang Wei

Abstract excerpt

Animal feeding is controlled by external sensory cues and internal metabolic states. Does it also depend on enteric neurons that sense mechanical cues to signal fullness of the digestive tract? Here, we identify a group of piezo-expressing neurons innervating the Drosophila crop (the fly equivalent of the stomach) that monitor crop volume to avoid food overconsumption. These neurons reside in the pars...

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Identifiers

PMID: 32910893
DOI: 10.1016/j.neuron.2020.08.017
PMCID: PMC8386590

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