Article
Molecular profiling of neuroendocrine tumours to predict response and toxicity to peptide receptor radionuclide therapy.
The Lancet. Oncology - 1 Sept 2020
Bodei Lisa, Schöder Heiko, Baum Richard P, Herrmann Ken, Strosberg Jonathan, Caplin Martyn, Öberg Kjell, Modlin Irvin M
Abstract excerpt
Peptide receptor radionuclide therapy (PRRT) is a type of radiotherapy that targets peptide receptors and is typically used for neuroendocrine tumours (NETs). Some of the key challenges in its use are the prediction of efficacy and toxicity, patient selection, and response optimisation. In this Review, we assess current knowledge on the molecular profile of NETs and the strategies and tools used to predict,...
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