Article
Long-term vemurafenib therapy in advanced melanoma patients: cutaneous toxicity and prognostic implications.
The Journal of dermatological treatment - 1 May 2022
Mandel Victor Desmond, Medri Matelda, Manganoni Ausilia Maria, Pavoni Laura, De Rosa Francesco, Ribero Simone, Foca Flavia, Andreis Daniele, Mazzoni Laura, Magi Serena, Farnetani Francesca, Palla Marco, Ulivi Paola, Stanganelli Ignazio
Abstract excerpt
BACKGROUND: The introduction of targeted therapies for the treatment of BRAF-mutated metastatic melanoma was associated with different cutaneous adverse events (AEs). OBJECTIVES: To describe the type, frequency and severity of cutaneous AEs related to vemurafenib; to understand the association between AEs and vemurafenib efficacy in terms of median overall survival (OS) and median progression-free survival (PFS);...
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