Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate.

Gut - 1 May 2021

van den Berg Fons F, van Dalen Demi, Hyoju Sanjiv K, van Santvoort Hjalmar C, Besselink Marc G, Wiersinga Willem Joost, Zaborina Olga, Boermeester Marja A, Alverdy John

Abstract excerpt

OBJECTIVE: The gut microbiota are the main source of infections in necrotising pancreatitis. We investigated the effect of disruption of the intestinal microbiota by a Western-type diet on mortality and bacterial dissemination in necrotising pancreatitis and its reversal by butyrate supplementation. DESIGN: C57BL/6 mice were fed either standard chow or a Western-type diet for 4 weeks and were then subjected to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Butyrates
Share to Diet, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Disease Progression

Share to Gastrointestinal Microbiome

Share to Mice, Inbred C57BL

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 32873697
DOI: 10.1136/gutjnl-2019-320430
PMCID: PMC7917160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate.PMID 32873697Read ↗

The alterations of gut microbiota in mice with chronic pancreatitisSemantic proximity Read ↗

Clostridium butyricum Strains Suppress Experimental Acute Pancreatitis by Maintaining Intestinal HomeostasisSemantic proximity Read ↗

Integrative metagenomic and metabolomic analyses reveal the potential of gut microbiota to exacerbate acute pancreatitisSemantic proximity Read ↗

The effect of butyrate-supplemented parenteral nutrition on intestinal defence mechanisms and the parenteral nutrition-induced shift in the gut microbiotaSemantic proximity Read ↗

Butyrate-producing human gut symbiont, Clostridium butyricum , and its role in health and diseaseSemantic proximity Read ↗

The fecal microbiota of patients with pancreatic ductal adenocarcinoma and autoimmune pancreatitis characterized by metagenomic sequencingSemantic proximity Read ↗

Metagenomics reveals functional profiles of gut microbiota during the recovery phase of acute pancreatitisSemantic proximity Read ↗

Dietary butyrate ameliorates metabolic health associated with selective proliferation of gut Lachnospiraceae bacterium 28-4Semantic proximity Read ↗

Intestinal microbiota enhances pancreatic carcinogenesis in preclinical modelsSemantic proximity Read ↗

Therapeutic Potential of Butyrate for Treatment of Type 2 DiabetesSemantic proximity Read ↗

Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in PSCSemantic proximity Read ↗

Correlation between Protection against Sepsis by Probiotic Therapy and Stimulation of a Novel Bacterial PhylotypeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.