Article
The turn to controls and the refinement of the concept of hereditary burden: The 1895 study of Jenny Koller.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2020
Kendler Kenneth S, Klee Astrid
Abstract excerpt
Throughout the 19th century, many alienists reported the proportion of their patients who were "hereditarily burdened," meaning they had a positive family history for mental illness. The rates of such burden differed widely because different authors used divergent definition of illness and investigated different groups of relatives. Most importantly, no authors compared rates of burden with those seen in a...
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