Using nuclear envelope mutations to explore age-related skeletal muscle weakness.

Abstract excerpt

Skeletal muscle weakness is an important determinant of age-related declines in independence and quality of life but its causes remain unclear. Accelerated ageing syndromes such as Hutchinson-Gilford Progerin Syndrome, caused by mutations in genes encoding nuclear envelope proteins, have been extensively studied to aid our understanding of the normal biological ageing process. Like several other pathologies...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aging
• Share to Lamin Type A
• Share to Membrane Proteins