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Article

Complement's favourite organelle—Mitochondria?

25 Aug 2020

Abstract excerpt

The complement system, well known for its central role in innate immunity, is currently emerging as an unexpected, cell-autonomous, orchestrator of normal cell physiology. Specifically, an intracellularly active complement system-the complosome-controls key pathways of normal cell metabolism during immune cell homeostasis and effector function. So far, we know little about the exact structure and localization of...

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PMID: 32840864
DOI: 10.1111/bph.15238

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