Article
Analysis of the Function of the Lymphocytic Choriomeningitis Virus S Segment Untranslated Region on Growth Capacity In Vitro and on Virulence In Vivo.
Viruses - 16 Aug 2020
Taniguchi Satoshi, Yoshikawa Tomoki, Shimojima Masayuki, Fukushi Shuetsu, Kurosu Takeshi, Tani Hideki, Fukuma Aiko, Kato Fumihiro, Nakayama Eri, Maeki Takahiro, Tajima Shigeru, Lim Chang-Kweng, Ebihara Hideki, Kyuwa Shigeru, Morikawa Shigeru, Saijo Masayuki
Abstract excerpt
Lymphocytic choriomeningitis virus (LCMV) is a prototypic arenavirus. The function of untranslated regions (UTRs) of the LCMV genome has not been well studied except for the extreme 19 nucleotide residues of both the 5' and 3' termini. There are internal UTRs composed of 58 and 41 nucleotide residues in the 5' and 3' UTRs, respectively, in the LCMV S segment. Their functional roles have yet to be elucidated. In...
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