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Article

KCND3-Related Neurological Disorders: From Old to Emerging Clinical Phenotypes.

International journal of molecular sciences - 13 Aug 2020

Pollini Luca, Galosi Serena, Tolve Manuela, Caputi Caterina, Carducci Carla, Angeloni Antonio, Leuzzi Vincenzo

Abstract excerpt

KCND3 encodes the voltage-gated potassium ion channel subfamily D member 3, a six trans-membrane protein (Kv4.3), involved in the transient outward K+ current. KCND3 defect causes both cardiological and neurological syndromes. From a neurological perspective, Kv4.3 defect has been associated to SCA type 19/22, a complex neurological disorder encompassing a wide spectrum of clinical features beside ataxia. To...

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Identifiers

PMID: 32823520
DOI: 10.3390/ijms21165802
PMCID: PMC7461103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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KCND3-Related Neurological Disorders: From Old to Emerging Clinical Phenotypes.PMID 32823520Read ↗

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