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Modelling Toxoplasma gondii infection in human cerebral organoids

1 Jan 2020

Abstract excerpt

Pluripotent stem cell-derived cerebral organoids have the potential to recapitulate the pathophysiology of in vivo human brain tissue, constituting a valuable resource for modelling brain disorders, including infectious diseases. Toxoplasma gondii, an intracellular protozoan parasite, infects most warm-blooded animals, including humans, causing toxoplasmosis. In immunodeficient patients and pregnant women,...

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PMID: 32820712
DOI: 10.1080/22221751.2020.1812435

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