Article
Epigenome-wide analysis uncovers a blood-based DNA methylation biomarker of lifetime cannabis use.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2021
Markunas Christina A, Hancock Dana B, Xu Zongli, Quach Bryan C, Fang Fang, Sandler Dale P, Johnson Eric O, Taylor Jack A
Abstract excerpt
Cannabis use is highly prevalent and is associated with adverse and beneficial effects. To better understand the full spectrum of health consequences, biomarkers that accurately classify cannabis use are needed. DNA methylation (DNAm) is an excellent candidate, yet no blood-based epigenome-wide association studies (EWAS) in humans exist. We conducted an EWAS of lifetime cannabis use (ever vs. never) using...
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