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Article

GBP5 Is an Interferon-Induced Inhibitor of Respiratory Syncytial Virus.

Journal of virology - 14 Oct 2020

Li Zhaolong, Qu Xinglong, Liu Xin, Huan Chen, Wang Hong, Zhao Zhilei, Yang Xu, Hua Shucheng, Zhang Wenyan

Abstract excerpt

Guanylate binding protein 5 (GBP5) belongs to the GTPase subfamily, which is mainly induced by interferon gamma (IFN-γ) and is involved in many important cellular processes, including inflammasome activation and innate immunity against a wide variety of microbial pathogens. However, it is unknown whether GBP5 inhibits respiratory syncytial virus (RSV) infection. In this study, we identified GBP5 as an effector of...

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Identifiers

PMID: 32796072
DOI: 10.1128/JVI.01407-20
PMCID: PMC7565618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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