Article
Multidirectional Strategies for Targeted Delivery of Oncolytic Viruses by Tumor Infiltrating Immune Cells.
Pharmacological research - 1 Nov 2020
Osali Abdolreza, Zhiani Mina, Ghaebi Mahnaz, Meymanat Mohammadreza, Esmaeilzadeh Abdolreza
Abstract excerpt
Oncolytic virus (OV) immunotherapy has demonstrated to be a promising approach in cancer treatment due to tumor-specific oncolysis. However, their clinical use so far has been largely limited due to the lack of suitable delivery strategies with high efficacy. Direct 'intratumoral' injection is the way to cross the hurdles of systemic toxicity, while providing local effects. Progress in this field has enabled the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
