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Article

Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue.

PLoS pathogens - 1 Aug 2020

Bayram Jan, Malcova Ivana, Sinkovec Larisa, Holubova Jana, Streparola Gaia, Jurnecka David, Kucera Jan, Sedlacek Radislav, Sebo Peter, Kamanova Jana

Abstract excerpt

Bordetella bronchiseptica and Bordetella pertussis are closely related respiratory pathogens that evolved from a common bacterial ancestor. While B. bronchiseptica has an environmental reservoir and mostly establishes chronic infections in a broad range of mammals, B. pertussis is a human-specific pathogen causing acute pulmonary pertussis in infants and whooping cough illness in older humans. Both species employ...

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Identifiers

PMID: 32776984
DOI: 10.1371/journal.ppat.1008512
PMCID: PMC7446853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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