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Article

DOCK6 promotes chemo- and radioresistance of gastric cancer by modulating WNT/β-catenin signaling and cancer stem cell traits.

Oncogene - 1 Sept 2020

Chi Hsiang-Cheng, Tsai Chung-Ying, Wang Chia-Siu, Yang Huang-Yu, Lo Chien-Hui, Wang Won-Jing, Lee Kam-Fai, Lai Li-Yin, Hong Ji-Hong, Chang Yen-Fang, Tsai Ming-Ming, Yeh Chau-Ting, Wu Cheng Heng, Hsieh Ching-Chuan, Wang Lu-Hai, Chen Wei-Jan, Lin Kwang-Huei

Abstract excerpt

Gastric cancer (GC) is the third leading cause of cancer-related mortality worldwide and prognosis after potentially curative gastrectomy remains poor. Administration of GC-targeting molecules in combination with adjuvant chemo- or radiotherapy following surgical resection has been proposed as a potentially effective treatment option. Here, we have identified DOCK6, a guanine nucleotide exchange factor (GEF) for...

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PMID: 32753649
DOI: 10.1038/s41388-020-01390-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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