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Article

EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer

30 Jul 2020

Abstract excerpt

Engrailed-2 (EN2), a member of the engrailed homeobox family, has been shown to be abnormally expressed in a variety of cancers. However, the expression and the clinical significance of EN2 in colorectal cancer (CRC) are largely unknown. Firstly, we found that EN2 acted as an oncogene in CRC. EN2 was upregulated in colorectal cancer tissues compared with adjacent normal tissues. Higher EN2 expression was...

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PMID: 32732864
DOI: 10.1038/s41419-020-02804-3

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