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Article

The novel long noncoding RNA u50535 promotes colorectal cancer growth and metastasis by regulating CCL20

3 Jul 2018

Abstract excerpt

Long noncoding RNAs (lncRNAs) have been emerging as master regulators of tumor growth and metastasis, but the functions and underlying mechanisms of lncRNAs in colorectal cancer (CRC) still need to be clarified. Here, we found a novel lncRNA u50535, which was greatly overexpressed in CRC tissues and was associated with poor prognosis in CRC patients. Function studies showed that u50535 was an oncogene in CRC both...

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PMID: 29970882
DOI: 10.1038/s41419-018-0771-y

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