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Article

Characterization of two MHC II genes (DOB, DRB) in white-tailed deer (Odocoileus virginianus).

BMC genetics - 29 Jul 2020

Ivy-Israel Natascha M D, Moore Carolyn E, Schwartz Tonia S, Ditchkoff Stephen S

Abstract excerpt

BACKGROUND: The major histocompatibility complex (MHC) is responsible for detecting and addressing foreign pathogens inside the body. While the general structure of MHC genes is relatively well conserved among mammalian species, it is notably different among ruminants due to a chromosomal inversion that splits MHC type II genes into two subregions (IIa, IIb). Recombination rates are reportedly high between these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32727360
DOI: 10.1186/s12863-020-00889-5
PMCID: PMC7392685

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