Article
Prognostic Markers of Myelodysplastic Syndromes.
Medicina (Kaunas, Lithuania) - 27 Jul 2020
Veryaskina Yuliya Andreevna, Titov Sergei Evgenievich, Kovynev Igor Borisovich, Pospelova Tatiana Ivanovna, Zhimulev Igor Fyodorovich
Abstract excerpt
Myelodysplastic syndrome (MDS) is a clonal disease characterized by multilineage dysplasia, peripheral blood cytopenias, and a high risk of transformation to acute myeloid leukemia. In theory, from clonal hematopoiesis of indeterminate potential to hematologic malignancies, there is a complex interplay between genetic and epigenetic factors, including miRNA. In practice, karyotype analysis assigns patients to...
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