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Using Wolbachia to Eliminate Dengue: Will the Virus Fight Back?

15 Apr 2021

Abstract excerpt

Recent field trials have demonstrated that dengue incidence can be substantially reduced by introgressing strains of the endosymbiotic bacterium Wolbachia into Aedes aegypti mosquito populations. This strategy relies on Wolbachia reducing the susceptibility of Ae. aegypti to disseminated infection by positive-sense RNA viruses like dengue.

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PMID: 33853965
DOI: 10.1128/jvi.02203-20

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