Article
Evolutionary Stabilization of Cooperative Toxin Production through a Bacterium-Plasmid-Phage Interplay.
mBio - 21 Jul 2020
Spriewald Stefanie, Stadler Eva, Hense Burkhard A, Münch Philipp C, McHardy Alice C, Weiss Anna S, Obeng Nancy, Müller Johannes, Stecher Bärbel
Abstract excerpt
Colicins are toxins produced and released by Enterobacteriaceae to kill competitors in the gut. While group A colicins employ a division of labor strategy to liberate the toxin into the environment via colicin-specific lysis, group B colicin systems lack cognate lysis genes. In Salmonella enterica serovar Typhimurium (S. Tm), the group B colicin Ib (ColIb) is released by temperate phage-mediated bacteriolysis....
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