Article
SARS‐CoV‐2 S1 is superior to the RBD as a COVID‐19 subunit vaccine antigen
21 Jul 2020
Abstract excerpt
Since its emergence in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has developed into a global pandemic within a matter of months. While subunit vaccines are one of the prominent options for combating coronavirus disease 2019 (COVID-19), the immunogenicity of spike protein-based antigens remains unknown. When immunized in mice, the S1 domain induced much higher IgG and IgA antibody...
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